Sili Gloves are meant to be used as an everyday alternative to costly throw away gloves. As per that, they can be cleaned regularly using isopropyl alcohol. Using a lightly soaked paper towel or an alcohol prep pad, wipe the palm-side of the glove down and allow to air dry. The same can be done if necessary for the lycra on the knuckle-side of the glove. For tougher stains on the lycra, simply hold the rag over the area to allow the alcohol to break it up, and again wipe away.